Soluble T Cell Immunoglobulin Mucin Domain 3 Is Shed from CD8 + T Cells by the Sheddase ADAM10, Is Increased in Plasma during Untreated HIV Infection, and Correlates with HIV Disease Progression
نویسندگان
چکیده
منابع مشابه
An Efficient Method to Solve the Mathematical Model of HIV Infection for CD8+ T-Cells
In this paper, the mathematical model of HIV infection for CD8+ T-cells is illustrated. The homotopy analysis method and the Laplace transformations are combined for solving this model. Also, the convergence theorem is proved to demonstrate the abilities of presented method for solving non-linear mathematical models. The numerical results for $N=5, 10$ are presented. Several $hbar$-c...
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Mechanisms leading to the observed immune dysregulation in HIV-1 infection are not well understood. HIV-specific IL-10-positive CD8(+) T cells are increased in advanced HIV disease. We have previously reported that Gag-specific IL-10-positive CD8(+) T cells suppressed cytolysis. In this study we describe the suppressive effect of Nef-specific IL-10-positive CD8(+) T cells. Interestingly, simult...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2015
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.00006-15